Hypertension, as one of the most common chronic diseases, has become a major risk factor of cardiovascular diseases.Extensive studies indicate that aerobic exercise has the ability to lower blood pressure and to ameliorate the risk factors of hypertension, especially in individuals with higher baseline blood pressure and hypertensive patients.First, this paper reviews the beneficial effects of aerobic exercise on hypertension and the possible potential mechanisms.It means that aerobic exercise improves peripheral pressure, central artery pressure and cardiac function, having beneficial effects on arteriosclerosis, endothelial function and sympathetic nervous system activity.Then, the paper introduces the rules of establishing exercise prescriptions among hypertension patients and its differences between different human populations, such as gender, age, baseline blood pressure, etc.The risks brought by excessive exercise and certain avoidance methods are also discussed.Finally, according to the requirements of precision medicine, combined with the considerations of security, we provide certain directions of future comprehensive studies to prescribe personalized exercise programs.