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非肥胖健康成人静息代谢率预测公式准确性研究

Accuracy of predictive equations for resting metabolicrate in non-obese healthy Chinese adults

作者: 汪锡  王远  许杨  吴庆园  姚南  马祖长  孙怡宁 
单位:中国科学院合肥智能机械研究所运动与健康信息技术研究室(合肥230031)
关键词: 静息代谢率;预测公式;间接测热法;肥胖;准确性 
分类号:R318
出版年·卷·期(页码):2017·36·6(607-613)
摘要:

目的 静息代谢率(resting metabolic rate,RMR)预测公式是临床营养支持、防治肥胖中控制能量平衡的重要工具,而我国非肥胖健康成人的最佳预测公式尚不明确。本文将评估14个常见RMR预测公式的准确性,寻找适合该类人群的最佳预测公式。方法 招募了46名非肥胖的健康成年人作为受试者,利用间接测热法测量受试者的RMR,同时利用14个预测公式对其RMR进行估算。通过偏倚、准确率、均方根误差和一致性相关系数评估每个预测公式的准确性。结果 虽然H-B、Mifflin、WHO、Schofield、Livingston、Henry、Muller、Lazzer、De Lorenzo和Huang公式的偏倚较小(<5%),但个体层面的误差较大,准确率均不超过70%。预测准确率依次是Henry(69.6%)>Lazzer(67.4%)=H-B(67.4%)>Mifflin(65.2%)=Schofield(65.2%)=WHO(65.2%)=De Lorenzo(65.2%)>Muller(63.0%)>Livingston(60.9%),Bernstein公式(21.7%)的准确率最低。结论 对于我国非肥胖健康成年人,常见的14个RMR预测公式的准确性均不理想,相对而言,Henry公式准确性最高。在缺乏间接能量测试仪的情况下,Henry公式可作为替代方法。

Objective Predictive equations of resting metabolic rate(RMR)are important tools for control of energy balance in nutrition support and the prevention and treatment of obesity.However,the best one for non-obese healthy Chinese adults is unclear.Our objective is to examine the accuracy of 14 common RMR predictive equations and to find the best alternative for indirect calorimetry.Methods RMR was measured by indirect calorimetry and calculated by 14 predictive equations in 46 participants.Bias,accuracy rate,root mean squared prediction error and concordance correlation coefficient were used to evaluate accuracy of the predictive equations.Results Although the biases of H-B,Mifflin,WHO,Schofield,Livingston,Henry,Muller,Lazzer,De Lorenzo and Huang equations were small(<5%),they were less accurate in the individual level.All of the accuracy rates were no more than 70%.The Henry equation(69.6%)had the highest accuracy rate,followed by Lazzer(67.4%),H-B(67.4%),Mifflin(65.2%),Schofield(65.2%),WHO(65.2%),De Lorenzo(65.2%),Muller(63.0%)and Livingston(60.9%). Bernstein equation was the most inaccurate.Conclusions All of the 14 common predictive equations were not accurate enough in non-obese healthy Chinese adults.Henry equation was relatively the most accurate and may act as the best alternative for indirect calorimetry when indirect calorimetry was unavailable.

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