北京生物医学工程

一种便携式多部位超声骨密度测量仪的研究

Research on a portable ultrasonic bone densitometer for multiple sites

作者：许杨陈焱焱丁增辉徐玉兵马祖长孙怡宁

单位：中国科学院智能机械研究所（合肥 230031）中国科学技术大学自动化系（合肥 230026）

关键词：骨密度; 定量超声; 便携式; 桡骨; 胫骨; 骨质疏松

分类号：R318.6

出版年·卷·期（页码）：2018·37·2（193-196）

摘要：

Objective We developed a new ultrasound densitometer to estimate bone mineral density accurately at radius and tibia, and compared the values of ultrasound measurements obtained in a clinical study with gold standard measurement: dual-energy X-ray absorptiometry (DEXA) to determine the validity of the new device. Methods The probe was designed based on ultrasonic axial-transmission technology by using doubleemission and double-receiving mechanism. A temperature sensor was used to amend the results in the ultrasound measurements. Twenty five subjects aged 35. 5 years ± 11. 7 years were recruited for this study. The ultrasound parameters (SOSFAS-radius, SOSFAS-tibia) of each subject were measured in the distal 1/3 radius and middle tibia respectively, and bone mineral density (BMD) at the lumbar spine (the vertebral levels L2-L4) was measured. Pearson's correlation coefficient was used to assess the relationships between the two ultrasound parameters and BMD. Results The correlation coefficients of SOSFAS-radiusand SOSFAS-tibiawith BMD were r = 0. 68 (P<0. 001) , and r= 0. 77 (P<0. 001) , respectively. Conclusions The parameters measured by the new device and BMD measured by DXEA were significantly correlated. Moreover, the device was designed at low cost and portable, which enable the popularization of osteoporosis diagnosis and monitoring, to provide an effective means for the screening of osteoporosis in large population-based.

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