北京生物医学工程

便携式生物阻抗相位角测量仪

Portable bio-impedance phase angle measuring instrument

作者：马鸿斌田常正蔡希昌霍小林张广浩

单位：北方工业大学（北京 100144）<p>中国科学院电工研究所（北京100190）</p>

关键词：生物阻抗相位角；人体成分； AFE4300； STM32；锂电池

分类号：R318.04，TN98

出版年·卷·期（页码）：2019·38·1（89-95）

摘要：

目的设计一台便携式的生物阻抗相位角测量仪，用于分析人体各身体成分及营养状况。方法为提高测量仪测量精度和数据分析能力，采用八电极分段阻抗测量方法，通过计算即可得到身体分段的阻抗。采用TI公司生产的AFE4300高集成度前端方案，以提高其便携性和测量精度。该测量仪主要分为6个部分，分别是AEF4300芯片集成前端、STM32单片机电路、有机发光二极管（organic light-emitting diode，OLED）显示器、电池及电源电路、USB数据传输电路及Flash数据存储器。其中，AFE4300集成前端实现电极的驱动与测量、ADC转换和IQ解调等功能；STM32 单片机用于控制整个测量仪；OLED显示器进行数据显示；电池及电源电路通过低压差线性稳压器（low dropout regulator，LDO）技术实现并采用锂电池供电；USB数据传输电路实现数据的上传和锂电池的充电功能；Flash数据存储器用于存储测量数据和校准数据。结果通过对人体阻抗RC三元件模型的测量验证，该测量仪在阻抗模测量和相位角测量方面的误差分别低于2%和4%。通过对志愿者实测，测量时间约为30s，符合相关文献数据。结论该测量仪的精度和测量速率都可以满足实用化要求，具有一定的市场价值。

Objective To design a portable bio-impedance phase angle measurement system for the analysis of human body composition and nutritional status. Methods In order to improve the measurement accuracy and data analysis ability, the measuring instrument uses the eight-electrode segment impedance measurement method, through the calculation can get the impedance of body segment. To improve the portability and measurement accuracy, TI's AFE4300 highly integrated front-end program is used. The measuring instrument is divided into six parts, they are AEF4300 chip integrated front end, STM32 microcontroller circuit, OLED (organic light-emitting diode) display, battery and power supply circuit, USB data transmission circuit and flash data memory. Among them, AFE4300 integrated front-end is uesd to achieve the electrode drive and measurement, ADC conversion and IQ demodulation and other functions. STM32 MCU is used to control the whole measuring instrument, OLED is used to display the data, battery and power circuit supplied by lithium battery works according to the principle of LDO,USB data transmission circuit is used to achieve data upload and lithium battery charging function;flash data memory is used to store measurement data and calibration data. Results Through the measurement of the RC three component model of human body impedance, the error of the measuring instrument in impedance mode measurement and phase angle measurement is less than 2% and 4% respectively. Through the measurement of volunteers, the measurement time is about 30 seconds, basically consistent with the relevant literature data. Conclusions The above test proved that the accuracy of the measuring instrument and measurement rate can meet the practical requirements, so it has a certain market value.

参考文献：

[1]祁朋祥.基于生物电阻抗的人体成分测试与研究[D].合肥：中国科学技术大学,2009.

Qi PX. Human body composition testing and research based on bioelectrical impedance [D].Hefei: University of Science and Technology of China, 2009.

[2]赵深林,牟东兰.人体成分测量装置的设计[J].电子产品世界,2009,16(9):53-55,62.

Zhao SL, Mou DL. Design of body composition measuring device [J].Electronic Engineering & Product World for Engineering Managers & Designers, 2009, 16(9):53-55,62.

[3]Zhang GH, Huo XL, Wu CZ, et al. A bioelectrical impedance phase angle measuring system for assessment of nutritional status [J].Bio-Medical Materials and Engineering, 2014, 24(6):3657–3664.

[4]罗仕强,田华,黄华.基于单片机的生物电阻抗频谱测量系统[J].现代电子技术, 2009, 32(12):146-148,151.

Luo SQ, Tian H, Huang H. Bioelectrical impedance frequency spectrum measurement system based on single chip computer [J].Modern Electronics Technique, 2009, 32(12):146-148,151.

[5]Kyle Ursula G, Bosaeus Ingvar, De Lorenzo Antonio D, et al. Bioelectrical impedance analysis--part I: review of principles and methods [J]. Clinical Nutrition, 2004, 23(5):1226-1243.

[6]高秀娥,唐佳,陈波.多频多段人体生物电阻抗测量系统[J].测控技术,2012,31(4):122-124,129.

Gao XE, Tang J, Chen B .A bioelectrical impedance measurement system based on multi-frequency and multi-segment technology [J]. Measurement & Control Technology, 2012, 31(4):122-124,129.

[7]吴国豪,吴肇汉,吴肇光.应用生物电阻抗分析法检测营养不良病人的人体组成[J].肠外与肠内营养, 2002, 9(2):87-89,93.

Wu GH, Wu ZH, Wu ZG. Use of bioelectrical impedance analysis measurement in malnutrition patients [J]. Parenteral & Enteral Nutrition, 2002, 9(2):87-89,93.

[8]林凌,王斯亮,李刚.基于AD5933的高精度生物阻抗测量方法[J].电子产品世界,2008,(7):74.

Lin L, Wang SL, Li G .High precision bio-impedance measurement method based on AD5933 [J]. Electronic Engineering & Product World, 2008, (7):74.

[9]刘胜洋.生物电阻抗测量的理论探讨[J]. 微计算机信息,2011,(11):44-45,56.

Liu SY, Academic discussion about bioelectricity measurement [J].Microcomputer Information, 2011, (11):44-45,56.

[10]黄海滨,任超世.生物电阻抗分析法测量人体成分[J]. 国外医学：生物医学工程分册,2000,23(3):151-155.

Huang HB, Ren SC. Measurement of body composition by bioelectrical impedance analysis [J].Foreign Medical Sciences：Biomedical Engineering Fascicle ,2000,23(3):151-155.

[11]郑新玲.使用一次性心电电极片应注意的问题[J]. 医疗装备,2002,15(10):21.

[12]侯少华,李旭鸿,郑秀媛.运用生物电阻抗法对成年人人体成分的研究[J]. 体育科研,2006,27(2):80-82.

[13]周弘,邹远文,李晋川.生物电阻抗测量中的信号发生模块设计[J].实验科学与技术,2012,10(1):31-33.

Zhou H, Zhou WY, Li JC. Signal generator for bioelectrical impedance measurement [J].Experiment Science and Technology, 2012,10(1):31-33.

[14]赵进创,黎志刚,刘金花,等.生物电阻抗测量系统中同时多频混合激励源的设计[J].计算机测量与控制, 2011, 19(10):2482-2484.

Zhao JC, Li ZG, Liu JH, et al. Design of multi-frequency-one-time current source for biological electrical impedance measurement System [J].Computer Measurement & Control, 2011, 19(10):2482-2484.

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