北京生物医学工程

腹主动脉瘤计算机仿真研究进展

Progress of computer simulation in abdominal aortic aneurysm

作者：杨冯棱郭立王依影

单位：昆明医科大学第二附属医院放射科(昆明 650101）

关键词：腹主动脉瘤; 计算流体力学; 血流动力学; 生物力学; 数值模拟

分类号：R318.04

出版年·卷·期（页码）：2019·38·2（212-217）

摘要：

腹主动脉瘤(abdominal aortic aneurysm , AAA)是腹主动脉较常见的疾病，破裂之后致死率极高，因此，及时发现和评估AAA破裂的风险就具有重要意义。近年来随着医学影像、计算机及血流动力学等理论和技术的快速发展，利用计算机模拟技术对AAA进行仿真研究已成为研究的热点，其模拟的结果趋于人体真实的动脉瘤，并在揭示AAA的发生及演变的机制方面发挥了重要作用。本文介绍了AAA仿真研究的原理及模型分类，详细地阐述了瘤体形态、瘤壁的结构及属性、血液及血流的属性、腔内血栓等相关因素在仿真研究中的作用，并对其目前的进展及局限性予以综述。

Abdominal aortic aneurysm (AAA) is a common disease of abdominal aorta, its mortality rate is very high when ruptured. Therefore, it is of great significance to timely detect and assess the risk of rupture of AAA. Recently, with the rapid development of medical imaging technology, computer technology and hemodynamics theories, the simulation study of AAA has become a hot research topic. The simulation results are increasingly close to the real aneurysms of human and play a significant role in revealing the mechanism of the origin and evolution of AAA. Therefore, this paper introduces the principle and model classification of simulation of AAA, expounds detailedly the role of geometry, blood vessel wall structure and properties, properties of blood and blood flow, intraluminal thrombus and other related factors in simulation study, and summarizes the current progress and limitation.

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