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皮肤黏弹性的体内检测方法研究现状与展望

Research status and prospect of in vivo measurement of skin viscoelasticity

作者: 陆思宇  曲晓威  张彤  宋义林 
单位:黑龙江大学 机电工程学院(哈尔滨 150080)
关键词: 皮肤;  黏弹性;  检测方法;  印压法;  生物力学 
分类号:R318.01
出版年·卷·期(页码):2020·39·1(96-102)
摘要:

皮肤黏弹性作为皮肤组织的重要生物力学特性,对生理病理状态的分析、诊断、治疗有着极其重要的参考价值和指导作用,是评价皮肤功能的重要指标。近年来,随着生活水平的日渐提高和家庭护理需求的不断提升,人们越来越重视皮肤的美容、保健与护理。因此,与人体皮肤黏弹性相关的体内检测方法得到了广泛关注,皮肤黏弹性体内检测装置的研发也有了进一步推进。本文阐述了各类皮肤黏弹性体内检测方法的原理与技术发展历程,归纳了各种检测方法的优缺点并做了对比分析,最后对皮肤黏弹性未来的研究方向进行了展望。

 Viscoelasticity is considered as an important biomechanical property of skin, which plays an extremely important role in the whole procedure of evaluation, research, and treatment of dermal problems. In recent years, with the improvement of living standards and the increasing demand for family care, people pay more and more attention to skin beauty, health care and nursing. Thus, in vivo skin viscoelasticity detection technology of human skin has been widely concerned, which has further accelerated the development of in vivo skin viscoelasticity detection device.  In this paper, the principle and technological development of various skin viscoelasticity in vivo detection methods are described, the advantages and disadvantages of the detection methods are summarized and compared, and the future research directions are prospected.

参考文献:

[1] 卢天健, 徐峰. 皮肤的力学性能概述[J].力学进展, 2008, 38(4):393-426.

Lu TJ, Xu F. Mechanical properties of skin:a review [J]. Advances in Mechanics, 2008, 38(4):393-426.

[2] 成海平,刘正津,何光篪. 生物软组织力学活体测试技术进展[J]. 力学进展, 1995, 25(3):401-409.

Cheng HP, Liu ZJ, He GC, et al. The experimental approaches on the technique of measuring the mechanical properties of soft tissues in vivo [J]. Advances in Mechanics. 1995, 25(3):401-409.

[3] 王志超, 赵恒义, 杨黎明. 压缩载荷作用下皮肤的生物力学特性[J]. 宁波大学学报(理工版), 2015,28(4):64-69.

Wang ZC,Zhao HY,Yang LM. Biomechanical property of the skin under compressive load [J].Journal of Ninbo University(NSEE), 2015,28(4):64-69.

[4] 吴新丰, 康国政, 钱林茂. 猪背部皮肤生物力学特性的实验研究[J]. 医用生物力学,2009,24(6):452-457.

Wu XF,Kang GZ,Qian LM .Experimental study on biomechanical property of the skin in pig's back[J]. Journal of Medical Biomechanic,2009, 24(6):452-457.

[5] Kvistedal YA , Nielsen PMF . Estimating material parameters of human skin in vivo[J]. Biomech Model Mechanobiol, 2009, 8(1):1-8.

[6] Hiroshi O , Shigemi K , Midori O , et al. Use of cutometer area parameters in evaluating age-related changes in the skin elasticity of the cheek.[J]. Skin Research & Technology, 2013, 19(1):238-242.

[7] Qu D,Leverett JC , Mayne JR . Cutometer皮肤弹性分析方法的开发与应用[C]// 第七届中国化妆品学术研讨会论文集. 北京:中国香料香精化妆品工业协会, 2008:238-243.

Qu D, Mayne JR , Seehra GP , et al. Development and application of novel viscoelastic parameters in cutometer[C].Proceedings of the 7th China cosmetic symposium.Beijing:China Association of Fragrance Flavour and Cosmetic Industries ,2008:238-243.

[8] Luebberding S , Krueger N , Kerscher M . Quantification of age-related facial wrinkles in men and women using a three-dimensional fringe projection method and validated assessment scales[J]. Dermatologic Surgery, 2014, 40(1):22-32.

[9] 程方, 高金平, 杨森, 等. 汉族人群皮肤弹性与年龄和部位的相关性分析[J]. 中国美容医学, 2017,26(2):61-64.

Cheng F, Gao JP, Yang S, et al. Age-related and regional changes in skin elasticity: a quantitative evaluation of han subjects [J]. Chinese Journal of Aesthetic Medicine, 2017,26(2):61-64.

[10] 黄燕平, 郑永平. 组织弹性测量之传统印压测试[J]. 中国医疗设备, 2011,26(7):1-12.

Huang YP, Zheng YP. Traditional indentation test for measurement of soft tissue elasticity [J].China Medical Devices, 2011,26(7):1-12.

[11] 寇良朋, 孙中圣, 刘源峰, 等. 动态载荷下手指非线性响应实验研究[J]. 机械制造与自动化, 2013, 42(5):7-9.

Kou LP, Sun ZS, Liu YF, et al. Experimental study of finger nonlinear response under dynamic loading[J]. Mechanical Building & Automation, 2013, 42(5): 7-9.

[12] 胡伟, 汪道辉, 陈科,等. 软组织压弹性模量力学测量装置的设计[J]. 实验科学与技术, 2015, 13(4):19-21. 

Hu W, Wang DH, Cheng K, et al. Scheme for mechanical measuring device used to the compression elasticity of soft tissue [J] Experimental Science and Technology, 2015, 13(4):19-21.

[13] 王恒, 桑元俊. 动态微印压方法前臂皮肤黏弹性属性测量[J]. 科学技术与工程, 2017,17(3):164-168.

Wang H , Sang YJ. Measurement of viscoelastic properties of forearm skin based on dynamic micro indentation method[J]. Science Technology and Engineering, 2017,17(3): 164-168.

[14] Zheng YP , Mak AFT . Extraction of quasi-linear viscoelastic parameters for lower limb soft tissues from manual indentation experiment[J]. Journal of Biomechanical Engineering, 1999, 121(3):330-339.

[15] Schade PDH . Untersuchungen zur organfunction des bindegewebes[J]. Zeitschrift Für Experimentelle Pathologie Und Therapie, 1913, 14(1):1-29.

[16] Kirk E , Kvorning SA . Quantitative measurements of the elastic properties of the skin and subcutaneous tissue in young and old individuals[J]. Journal of Gerontology, 1949, 4(4):273-284.

[17] Lewis HE , Mayer J , Pandiscio AA . Recording skinfold calipers for the determination of subcutaneous edema [J]. Journal of Clinical Laboratory Analysis, 1965,66(1):154-160.

[18] Mak AFT , Liu GHW , Lee SY . Biomechanical assessment of below-knee residual limb tissue[J].The Journal of Rehabilitation Research and Development, 1994, 31(3):188-198.

[19] Pathak AP, Silver-Thorn MB, Thierfelder CA, et al. A rate-controlled indentor for in vivo analysis of residual limb tissues [J]. IEEE transactions on rehabilitation engineering:a publication of the IEEE Engineering in Medicine and Biology Society, 1998,6(1):12-20.

[20] Klaesner JW , Commean PK , Hastings MK , et al. Accuracy and reliability testing of a portable soft tissue indentor[J]. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2001, 9(2):232-240.

[21] Lu MH , Yu W , Huang QH , et al. A hand-held indentation system for the assessment of mechanical properties of soft tissues in vivo[J]. IEEE Transactions on Instrumentation and Measurement, 2009, 58(9):3079-3085. 

[22] Gefen A, Megido-ravid M, Itzchak Y. In vivo biomechanical behavior of the human heel pad during the stance phase of gait[J]. Journal of Biomechanics, 2002, 34(12):1661-1665.

[23] Laasanen MS, T, J, Hirvonen J, et al. Novel mechano-acoustic technique and instrument for diagnosis of cartilage degeneration[J]. Physiological Measurement, 2002, 23(3):491-503.

[24] Li X, Wang G, Huang L, et al. Young\"s modulus extraction methods for soft tissue from ultrasound measurement system[J]. Instrumentation Science & Technology, 2006, 34(4):393-404.

[25] 王立科,郑永平,黄燕平,等.应用于组织力学性能分析的光学印压系统研究[J].中国医疗设备,2011,26(1):22-24.

Wang LK, Zheng YP, Huang YP, et al. Optical indentation system for analysis of the mechanical properties of tissue[J]. China Medical Devices,2011,26(1): 22-24.

[26] Liu H, Li J, Song X, et al. Rolling indentation probe for tissue abnormality identification during minimally invasive surgery[J]. IEEE Transactions on Robotics, 2011, 27(3):450-460. 

[27] Lu MH , Zheng YP , Huang QH . A novel noncontact ultrasound indentation system for measurement of tissue material properties using water jet compression[J]. Ultrasound in Medicine and Biology, 2005, 31(6):817-826.

 [28] Huang YP, Zheng YP, Wang SZ, et al. An optical coherence tomography (OCT)-based air jet indentation system for measuring the mechanical properties of soft tissues[J]. Measurement Science and Technology, 2009, 20(1):1-11.

[29] 邓辉胜,黄晶,李进嵩,等.介入超声印压系统的压力和超声校验研究[J].医疗设备信息,2007,22(7):2-4.

Deng HS, Huang J, Li JS, et al. Discussion on checking the pressure and ultrasound of intervention supersonic indentation system[J]. Information of Medical Equipment,2007,22(7):2-4.

[30] 王晴. 液体加载式皮肤软组织生物力学测试仪的研制与应用[D]. 第三军医大学, 2009.

Wang Q. Development and application of a novel liquid-loading device for biomechanical testing on skin tissue[D]. The Third Military Medical University, 2009.

[31] Srinivasan S, Krouskop T, Ophir J. Comparing elastographic strain images with modulus images obtained using nanoindentation: preliminary results using phantoms and tissue samples[J]. Ultrasound in Medicine & Biology, 2004, 30(3):329-343.

[32] Li C, Pruitt LA, King KB. Nanoindentation differentiates tissue-scale functional properties of native articular cartilage[J]. Journal of Biomedical Materials Research, 2006, 78(4):729-738.

[33] Grant CA, Twigg PC, Tobin DJ. Static and dynamic nanomechanical properties of human skin tissue using atomic force microscopy: effect of scarring in the upper dermis[J]. Acta Biomaterialia, 2012, 8(11):4123-4129.

[34] Gennisson JL, Baldeweck T, Tanter M, et al. Assessment of elastic parameters of human skin using dynamic elastography[J]. IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, 2004, 51(8):980-989.

[35] Omata S , Terunuma Y . New tactile sensor like the human hand and its applications[J]. Sensors and Actuators A (Physical), 1992, 35(1):9-15.

[36] Ishihara H, Sugo Y, Tsutsui M, et al. The ability of a new continuous cardiac output monitor to measure trends in cardiac output following implementation of a patient information calibration and an automated exclusion algorithm[J]. Journal of Clinical Monitoring and Computing, 2012, 26(6):465-471.

[37] 郑永平, 黄燕平.生物组织弹性测量:技术、仪器和应用[J]. 中国医疗设备, 2011, 26(5):1-15.

Zheng YP, Huang YP. Soft tissue elasticity measurement: techniques, instrument and applications [J]. China Medical Devices, 2011, 26(5):1-15.

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