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一种供液系统在线消毒方式的改进与研究

Improvement and research of online disinfection method of a liquid supply system

作者: 徐明明  吕庆文  白路花  
单位:南方医科大学生物医学工程学院 (广州510515)&nbsp; <p>南方医科大学珠江医院 (广州510282)</p> <p>通信作者:吕庆文,教授。E-mail: 1158407340@qq.com</p> <p>&nbsp;</p>
关键词: 集中供B液系统;模型设计;细菌污染;效果研究  
分类号:R318 <p>&nbsp;</p>
出版年·卷·期(页码):2022·41·2(185-189)
摘要:

目的 血透室集中供B液系统微生物时常难以控制,本文提出一种具有在线制、除臭氧、循环消毒及检测残余臭氧功能的B液供液装置以减少微生物的污染及节约消毒时间。方法 基于尽可能的模拟在配液、储液、供液过程中的实际应用,作者在康盛KCDS200-B型供液系统的基础上按 1:20 的比例改造设计出集中供B液小型模拟装置。装置根据在配液过程中是否进行臭氧消毒分为实验组和对照组并进行各 4 个周期的对比实验。每天分别对装置进行水体采样,通过统计其每毫升中细菌数量及变化来测试装置的臭氧消毒效果。结果 采用模型后对比康盛B液系统可节约消毒时间约3 h,在采用臭氧消毒后,装置细菌含量明显降低。消毒前和消毒后两组数据对比明显, 采用重复测量数据的两因素多水平分析的统计学方法,具有统计学意义(P〈0.05)。结论 集中供B液小型装置实现了B液中微生物的控制要求,改善了B液的污染状况,相比传统消毒方式更加便捷。

 

Objective The microorganisms of the blood permeable chamber centralized supply B-liquid system are often difficult to control, and this paper proposes a B-liquid supply device with on-line system, except ozone, circulating disinfection and detection of residual ozone function to reduce microbial pollution and save disinfection time. Methods Based on the practical application of the simulation in the process of dispensing, reservoir and supply as far as possible, the author designs a small simulation device with centralized B-liquid according to the ratio of 1:20 on the basis of Kangsheng KCDS200-B liquid supply system. The device is divided into experimental group and control group according to whether ozone disinfection is carried out in the dispensing process. The two groups performed a comparative experiment of 4 cycles each. The device is sampled daily by measuring the number of bacteria per milliliter and changes to test the ozone disinfection effect of the device.Results Comparing Kangsheng B liquid system after using the model can save disinfection time of about 3 hours, and after the use of ozone disinfection, the bacterial content is significantly reduced. The comparison between the two sets of data before and after disinfection is obvious, and the statistical method of multi-level analysis of two factors of repeated measurement data is used, which is of statistical significance (P < 0.05).Conclusions The small device of centralized B-liquid realizes the control requirements of microorganisms in B-liquid, improves the pollution of B-liquid, and is more convenient than the traditional disinfection method.

 

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