北京生物医学工程

生物组织收缩在微波消融术中的研究进展

Research progress of biological tissue shrinkage in microwave thermal ablation

作者：买欣南群胡昊田甄

单位：北京工业大学环境与生命学部生命科学与化学学院(北京  100124)<br />通信作者：南群，教授。E-mail: nanqun@ bjut. edu. cn

分类号：R318.04

出版年·卷·期（页码）：2023·42·1（94-99）

摘要：

微波消融治疗技术具有微创、操作简便、热效率高、患者耐受性好等优点，目前已经成为治疗肿瘤的重要手段。在微波消融过程中，不同生物组织受热会发生不同程度的收缩，影响到消融区域的大小。而生物组织消融区域对评估治疗疗效至关重要，同时在提高临床治疗的有效性和安全性方面也起着重要作用。因此，研究生物组织收缩具有重要的临床意义。本文首先分析了生物组织收缩的理论基础；其次对现有生物组织收缩的体外实验和数学模型进行了评估和分析；最后总结了目前相关生物组织收缩研究中所存在的局限性，并提出了今后的研究方向。

Microwave ablation(MWA) therapy technology has the advantages of minimal invasiveness, simple operation, high thermal efficiency, and good patient tolerance. It has become an important method for the treatment of tumors. During the microwave ablation process, different biological tissues will shrink to different degrees when heated, which affects the size of the ablation area. The area of biological tissue ablation is very important for evaluating the efficacy of treatment, and it also plays an important role in improving the effectiveness and safety of clinical treatment. Therefore, studying the shrinkage of biological tissues has important clinical significance. This article first analyzes the theoretical basis of biological tissue shrinkage; secondly, it evaluates and analyzes the in vitro experiments and mathematical models of the existing biological tissue shrinkage; finally, it summarizes the limitations of the current related biological tissue shrinkage research and proposes future researh directions.

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