北京生物医学工程

抗体包被对红细胞变形性影响的研究 _

Study on Deformability of Antibody—Coated Red Blood Cells

作者：宋立川; 吕智红; 马维原; 孙大公; 施岩; 高铁; 文宗曜;

单位：北京医科大学物理教研室;

关键词：红细胞; 变形性; 抗原; 抗体;

分类号：

出版年·卷·期（页码）：1995·1·2（99-102）

摘要：

作者对抗体包被的红细胞变性进行研究,发现抗体包被改变了红细胞的变形性。在我们研究的抗体量范围内,抗体量越多,红细胞的变形性越小。作者从血液流变学的角度对上述结果作了讨论,并提出了通过测定其对红细胞变形性的影响来比较准确地标定抗体效价的可能性。

Deformability of antibody-coated red blood cells was studied. The results showed that antibody-coated changed the deformability of red blood cells,and the more antibody (within the limit of antibody quantity we studies),the lower the erythrocytes deformability. The au thors discussed these results from the point of hemorheology, and suggested that the anti- serum titre can be determined relative accurately by measuring the changes of the red blood cells deformability index(DI).

参考文献：

中国期刊全文数据库共找到 1 条

[1]	文宗曜,陶祖莱,曹实,赵玉衡,李玉梅,徐家鸰,粟刚,于桂芬,刘淑华,吴本玠. 悬浮介质对红细胞变形性测量的影响[J]. 中国生物医学工程学报, 1992,(03) .

西文参考文献共找到 3 条

[1]	Clark MR,et al. Osmolality gradient ektacytometry:comprehensive characterization of red cell volume and surface mantenance .Blood, 1983, 61 :899 .
[2]	Ballas SK,et al. Rheological properties of antibody-coated red cell .Transfusion, 1984, 24 :124 .
[3]	Delamaire M. Is there a mechanical factor of haemolysis in patients with position IgG-type direct antiglobulin test .Bri J Haematol, 1992, 80 :91 .

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