In the process of pulmonary airway tree segmentation, it is prone to bronchial rupture and segmentation leakage, during to partial volume effects and noise pollution. In this paper, we proposed the hybrid method which was composed of optimal threshold region grow and morphology for pulmonary airway tree segmentation. Firstly the optimal threshold region growth algorithm was used to obtain low-level of airway tree, and the grayscale reconstruction morphological operator was used to extract fine potential regions of airway. Then by combining these two results of segmentation method, we obtained the integrated pulmonary airway tree. Lastly the method of region grow was used on integrated data set to remove pseudo-tracheal regions to ensure the three-dimensional connectivity of airway tree, including the trachea at level 5 and about 60% of the trachea at level 6. The proposed method effectively solved the problems of bronchial rupture and segmentation leakage, in the segmentation of high-precision airway tree, and had a good robustness.
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