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正常人颈动脉WI分析及其与左心室功能的关系

Wave Intensity in Carotid Artery and Its Relationship with Left Ventricular Function

作者: 张若冰  杨娅  李治安  勇强  曹燚 
单位:首都医科大学附属北京安贞医院(北京100029)
关键词: 波强度;颈动脉;左心室功能 
分类号:
出版年·卷·期(页码):2010·29·5(517-522)
摘要:

目的 对正常人颈动脉应用无创性波强度(wave intensity,WI)技术进行分析,并探讨其与左心室功能关系。方法 以34例健康人群为研究对象,行无创性WI检查,并将其与常规经胸超声心动图对比分析。结果 左、右两侧颈动脉WI各项指标间无统计学差异(P>0.05);收缩早期的WI(W1)与心脏射血分数(EF),与Simpson模式测得的舒张早期峰值速度(E)与舒张晚期峰值速度(A)的比值(E/A),与DTI模式获得的舒张早期峰值速度(E′)与舒张晚期峰值速度(A′)的比值(E′/A′)均呈正相关;比值E/E′与E′/A′呈负相关;收缩晚期的WI(W2)与比值E/A、E′/A′、E/E′均无明显相关性。结论 参数W1大小能反映左心室收缩功能,具有一定的临床应用价值;参数W2对于评价左室舒张功能具有局限性。应用无创WI技术评价左心室功能尤其是舒张功能方面有待更进一步的研究。

Aim To analyze the parameter of non-invasive wave intensity (WI) in carotid artery and discuss the relationship between WI and left ventricular function for healthy people. Methods Thirty-four healthy people were assessed by WI and conventional transthoracic echocardiography for left ventricular function. Results WI parameters between left and right carotids had no significant difference (P>0.05). The correlation analysis showed positive correlation between the early systolic WI(W1) and cardiac ejection fraction (EF), W1 and the ratio of early diastolic E and late diastolic A (E/A) in Simpson model . W1 and the ratio of early diastolic E′ and late diastolic A′ (E′/A′) in DTI model. The results showed the negative correlation between the ratio of E and E′ and the ratio of E′ and A′. However there were no significant correlations between end systolic WI(W2) and the radio of E and A, the ratio of E′ and A′, and the ratio of E and E′. Conclusion The parameters W1, which could reflect left ventricular systolic function, was valuable in clinic. The parameter W2 was not supposed for evaluation of left ventricular diastolic function. Further research is deserved in evaluating left ventricle function,  especially diastolic function by non-invasive wave intensity.

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