北京生物医学工程

改进的检测TWA的相关分析法

LI Tiantian,ZHAO Jie,LI Fei,GUO Hui

作者：李田田赵捷李斐郭慧

单位：山东师范大学物理与电子科学学院(济南250014)

分类号：

出版年·卷·期（页码）：2012·31·6（570-573）

摘要：

目的T波交替(T wave alternans,TWA)可独立预测室性心律失常与猝死，但传统的检测方法实时性较差。为实现短时T波交替的检测，提高实时性，本文利用改进的方法检测心电信号，为TWA信号的检测分析提供新手段。方法改进传统相关分析法中对齐时的模板及计算交替指数时的模板，待检测信号取自MIT-BIH和ST-T数据库。首先对待检测信号进行预处理，然后每两个相邻T波作为一组，先进行相关对齐，再计算交替指数，根据交替指数的判断规则判定是否存在T波交替，并用传统的谱分析法加以验证。结果成功实现了短时的T波交替检测，连续6个信号即可判断该段信号是否存在TWA现象，并通过了谱分析法的交替幅度值的验证，有更好的实时性。结论该方法可以用于短时的T波交替检测，计算方法简单，易于实现。本文还总结了影响T波交替检测的几个重要因素，直接计算相邻两T波间的交替相关指数是本文的创新点。
关键词T波交替；相关分析法；谱分析法；心电信号

Objective T wave alternans (TWA) can forecast ventricular arrhythmias and sudden death,however,the traditional method is not real-time. This paper proposes an improved method to detect short-time TWA. Methods We enhanced the traditional correlation method to detect T wave alternans,enhancing the template for alignment and calculating the alternans index. The data sets were taken from the MIT-BIH database and the ST-T database. After data preprocessing,we regarded each two adjacent T waves as a research group. Firstly we aligned the two T waves,calculated the alternans index,then to tell whether T wave alternans existing. Results This method realized the detection of short-time TWA and may judge TWA within six adjacent signals. Spectrum analysis was proposed to verify this improved method. Conclusions This improved correlation method could be used for detecting TWA. The algorithm was simple,easy to achieve. Certain important factors influencing the detection of TWA were discussed and the innovation point of the paper was the calculation for the alternans index of the two adjacent T waves.

参考文献：

［1］许培. T波店交替现象的临床意义［J］. 心电学杂志,2007,26(4)：255-259.
Xu Pei. The clinical significance of the T wave electric alternate phenomenon［J］. Journal of Electrocardiology,2007,26(4):255-259.
［2］许菲，滕炯华，张泾周. 体表心电图中T波交替现象的检测［J］. 北京生物医学工程，2011,30（4）:387-391.
Xu Fei,Teng Jionghua,Zhang Jingzhou. Detection of T-wave alternans in body surface ECG［J］. Beijing Biomedical Engineering，2011,30（4）:387-391.
［3］魏珑,赵捷,徐舫舟. 基于相关分析方法的非稳态心电T波交替检测研究［J］. 现代生物医学进展,2009,9(16):3128-3130.
Wei Long,Zhao Jie,Xu Fangzhou. Research on detecting the nonstationary T-wave alternans(TWA)based on correlation method［J］. Process in Modern Biomedicine,2009,9(16):3128-3130.
［4］Laura B,Silvia B，Roberto B. Correlation method versus enhanced modified moving average method for automatic detection of T-wave alternans. Computer Methods and Programs in Biomedicine. 2010,98(1):94-102.
［5］European ST-T database［EB/OL］. ［2011-05-04］. http://www. physionet. org/physiobank/database/edb/
［6］MIT-BIH arrhythmia database［EB/OL］. ［2011-06-12］. http://www. physionet. org/physiobank/database/mitdb/
［7］余辉,李恒达,张力新,等. 改进的谱分析法定量估算T波电交替的研究［J］. 中国生物医学工程学报， 2011,30(2):213-219.
Yu Hui,Li Hengda,Zhang Lixin,et al. Quantitative estimation of T-wave alternans based on an improved spectral technology［J］. Chinese Journal of Biomedical Engineering， 2011,30(2):213-219.
［8］徐舫舟,赵捷,王纪奎. T波交替散点图法：利用非线性动力学系统表示周期性的散点图［J］. 中国组织工程研究与临床康复,2010,14(9):1645-1648.
Xu Fangzhou,Zhao Jie,Wang Jikui. Poincare mapping method for T-wave alternans using a nonlinear dynamic system［J］. Journal of Clinical Rehabilitative Tissue Engineering Research,2010,14(9):1645-1648.
［9］张石,佘黎煌,徐中强，等. 心电T波电交替检测算法综述［J］. 中国生物医学工程学报,2010,29(3):446-453.
Zhang Shi,She Lihuang,Xu Zhongqiang,et al. A survey of the T wave alternans detection algorithms［J］. Chinese Journal of Biomedical Engineering,2010,29(3):446-453.

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