北京生物医学工程

超顺磁性四氧化三铁纳米颗粒的制备及表征

Preparation and characterization of super-paramagnetic Fe3O4nanoparticles

作者：蔡晓峰张黎明戴长松

单位：哈尔滨医科大学附属第一医院(哈尔滨150001）

分类号：

出版年·卷·期（页码）：2012·31·6（603-606）

摘要：

目的水热法制备超顺磁性四氧化三铁纳米颗粒，检测其物理学及磁学性质，并探讨其用于物理化学溶栓的可行性。方法水热法制备聚乙二醇6000包被的四氧化三铁颗粒，采用X射线衍射法分析其结构，用扫描电镜测量其直径及分布，用振动样品磁强计检测磁学参数。结果所得样品为四氧化三铁晶体，粒径为200nm，质量饱和磁场强度为79.8emu/g Fe。结论制备的样品粒径均一，分散性好，超顺磁性，水溶性好，可用于物理化学溶栓。

Objective To prepare super paramagnetic Fe3O4by hydrothermal method and test the physical and magnetic properties. Methods The Fe3O4 nanoparticles with PEG6000-coating is obtained by means of hydrothermal method,the structure is analyzed by X-ray powder diffraction method,the size and distribution is measured by transmission electron microscope,and the susceptibility is measured by Vibrating Sample Magnetometer dollars. Results The particle diameter size of the super paramagnetic Fe3O4 is 200nm. These particles possess some characteristics of super paramagnetism. The quality saturation magnetic intensity is 79.8emu/g Fe. Conclusions The samples are dispersed,water-soluble,super-paramagnetic and homogeneous in particle diameter,which can be used in physical chemistry thrombolysis.

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