设为首页 |  加入收藏
首页首页 期刊简介 消息通知 编委会 电子期刊 投稿须知 广告合作 联系我们
利用EMG运动单位动作电位数目估算法研究痉挛型脑瘫患儿神经元发放特性_________

cerebral palsy based on the estimation of motor unit action potential number in electromyography signal

作者:               姚博  杨基海  陈香  吴德  钱玲玲  周逸峰          
单位:           中国科学技术大学电子科学与技术系(合肥230027)    
关键词:           小儿脑瘫;表面肌电信号;运动单位动作电位数目估计;平滑非线性能量算子;平均发放间隔      
分类号:
出版年·卷·期(页码):2013·32·2(127-133)
摘要:

目的 小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法 采用平滑非线性能量算子(smoothed nonlinear energy operator,SNEO)算法,对痉挛型脑瘫患儿表面肌电信号中的运动单位动作电位(motor unit action potential,MUAP)数目进行估计,获得MUAP的平均发放间隔(inter-pulse interval,IPI),并根据医生采用的分级结果和健康人MUAP平均发放时限的早期研究结果进行对比验证。结果 对14名不同运动障碍级别脑瘫患者的实验结果显示,其肌电信号MUAP的IPI与他们活动度的级别即运动障碍的程度呈正相关的关系,且具有明显差异。结论 研究结果表明本文方法有效,采用IPI参数能够反映脑瘫患儿的运动障碍程度。

Objective The evaluation of dyskinesia and rehabilitation for cerebral-palsy(CP)patients is of important clinical value. The firing characteristics of motor neurons in child cerebral palsy are studied by means of surface electromyography(sEMG)to provide an index for CP patients. Methods The smoothed nonlinear energy operator(SNEO)algorithm is adopted to estimate the number of motor unit action potential(MUAP)in sEMG collected from CP patients. Then,inter-pulse interval(IPI)of MUAP is achieved. The results are verified by the diagnosis and early research on mean potential duration of healthy male volunteers. Results The results of 14 patients’ sEMG signals in different CP levels show that there is a positive correlation between their IPIs and the severity of the disease,which also means the levels of CP dyskinesia,and the differences in various CP levels are significant. Conclusions Experimental results of real CP sEMG signals demonstrate that this method is effective and IPI of MUAP can be used as quantitative index for the evaluation of CP dyskinesia and rehabilitation.

参考文献:

[1]王茂斌.神经康复学[M].北京:人民卫生出版社,2009:663-667.
Wang Maobin. Neurological Rehabilitation[M]. Beijing:People’s Medical Publishing House,2009:663-667.
[2]顾秀玲,周红瀛,柴增良,等. 脑瘫患儿332例临床资料与疗效分析[J]. 中国医药导报,2011,8(27):151-152.
Gu Xiuling,Zhou Hongying,Cai Zengliang,et al. Analysis of clinical data and therapeutic effects of 332 sick children with cerebral palsy patients[J]. China Medical Herald,2011,8(27):151-152.
[3]李强.表面肌电信号的运动单位检测[D].合肥:中国科技大学,2008.
Li Qiang. Study on the detection of motor unit action potentials in surface electromyography[D]. Anhui:USTC,2008.
[4]Blok JH, van Dijk JP,Drost G,et al. A high-density multichannel surface electromyography system for the characterization of single motor units[J]. Review of Scientific Instruments,2002,73(4):1887-1897.
[5]Zhang YM, Amin MG.Blind separation of nonstationary sources based on spatial time-frequency distributions[J]. EURASIP Journal on Applied Signal Processing,2006:1-13.
[6]Sudipta Mukhopadhyay, Ray GC. A new interpretation of nonlinear energy operator and its efficacy in spike detection [J]. IEEE Transactions on Biomedical Engineering,1998,45(2):180-187.
[7]雷培源, 杨基海,陈香. 一种基于三级滤波器的表面肌电信号降噪处理技术[J]. 北京生物医学工程,2011,30(1):62-66.
Lei Peiyuan,Yang Jihai,Chen Xiang. Surface electromyography denoising method based on three-level filter[J]. Journal of Biomedical Engineering,2011,30(1):62-66.
[8]李强,杨基海,陈香,等.基于非线性能量算子的表面肌电信号MUAP发放检测[J]. 北京生物医学工程,2006,25(4):376-380.
Li Qiang,Yang Jihai,Chen Xiang,et al. A MUAP onset detection method of surface EMG signal based on nonlinear energy operator[J]. Journal of Biomedical Engineering,2006,25(4):376-380.
[9]汤晓芙. 神经病学-神经系统临床电生理学:肌电图学及其他[M].北京:人民军医出版社,2002:75-78.
Tang Xiaofu. Neurology-clinical Electrophysiology of Nervous System:Electromyography and Others[M]. Beijing:People’s Military Medical Publisher,2002:75-78.

服务与反馈:
文章下载】【加入收藏
提示:您还未登录,请登录!点此登录
 
友情链接  
地址:北京安定门外安贞医院内北京生物医学工程编辑部
电话:010-64456508  传真:010-64456661
电子邮箱:llbl910219@126.com