Objective Accurate segmentation of brain tissue in MRI is an essential step and remains a challenging problem because of acquisition noise,non-uniformities in the MR magnetic field,partial volume effects and the complex anatomy structure of the brain. Methods In this paper,we presented a novel approach based on Random Walks (RW) to extract white matter (WM),gray matter (GM) and cerebrospinal fluid (CSF). To overcome the shortcomings of Random Walks,we introduced the concept of local binary patterns (LBP) into Random Walks to construct a new weighting function. The new weighting function not only reflected the changing information of adjacent-pixel’s gray value,but also contained the texture information of local image,which could strengthen the ability of RW to identify homogeneous pixels and edges. We also achieved a better performance with prior probability model. Results Experiment results were analyzed against different levels of noise and bias field,and the proposed method performed better discriminative power of identifying the brain tissue boundary. Conclusions This improved Random Walks based on LBP segments brain tissue images accurately.
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