Mild hypothermia therapy has been used as a method for protection of brain in the treatment of stroke and craniocerebral injury. This paper focused on the likely mechanism of brain protection,the technology of mild hypothermia and certain key problems in the research and application of mild hypothermia therapy. The brain-protecting effect of mild hypothermia therapy has been confirmed. The syndrome,the time window and temperature window,the dwell time and the rewarming rate of mild hypothermia therapy are still needed to discuss.
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