Objective To test the clinical value of AKM-N1 type portable remote real-time ECG monitor. Methods Thirty-six patients who were treated in intracardiac department of Beijing Anzhen Hospital from October to November in 2011 were involved in this trial. Arrhythmia was the main manifestation in these patients. There were 21 male cases and 15 female cases, and the average age was 43.0±14.8 years. All the patients underwent real-time ECG test and Holter monitor at the same time. The ECG data, including the duration of P wave, PR interval, QRS duration, QT interval, RR interval, artifacts, interference and arrhythmia type, were compared. The parameters of the two groups in the same time-point were selected, including the 10th min, 20th min, 30th min, 40th min and 50th min after beginning, as well as two time-points when the “capture key” were pressed synchronously as subjects had heart discomfort or just after the instruction of doctors. Results Arrhythmia was detected in 29 cases. There was no difference in ECG parameters of the two methods and the arrhythmia detection rate of the two methods was highly associated (P<0.001). There was no difference in the proportion of arrhythmia (P=1.0). The relevance of the two methods for detecting spuriousity and interference was not certain, yet the ratio had no difference. There was no adverse reaction in this trial. Conclusions AKM-N1 type portable remote real-time ECG monitor can provide accurate ECG data. The value on arrhythmia diagnosis is equal to that of Holter. Doctors can get the patients’ information and give them therapy advice on time with internet.