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一种新型输尿管支架管及磁性导尿管

A novel ureteral stent and the magnetic catheter

作者: 王瑨  黄赤兵  冯嘉瑜  胡文刚  许晓婷  宋亚军  孙帧  陈益荣  王平贤  范明齐                  
单位:                      第三军医大学新桥医院(重庆400037)        
关键词:                     输尿管支架管;磁性;拔除           
分类号:
出版年·卷·期(页码):2014·33·2(179-184)
摘要:

目的 设计一种末端带有可释放型纳米铁牵引线的新型输尿管支架管及磁性拔除导尿管,并初步评估这种新型拔管方法的可行性。方法 设计并制备新型输尿管支架管及磁性拔除导尿管,并对部件和材料进行性能测试,包括热失重分析测定纳米铁牵引线的铁含量、机械牵伸实验测定纳米铁牵引线断裂强度、磁强计测定导尿管磁性强度并检测磁性导尿管夹持力大小,以及新型输尿管拔除方法有效性检验,即在前期研制的透明泌尿系统模拟模型中进行拔除实验,统计拔除成功率及拔除阻力。结果 单位长度牵引线中纳米铁粉的质量分数约为23%,牵引线断裂强度为10.12 N,磁性导尿管磁性强度578 emu/g,磁性导尿管夹持力(10.79±0.84) N。新型输尿管支架管拔除成功率98%,拔除过程中最大阻力为(5.26± 0.53) N。结论 这种新型拔管方法有效可行,且现有材料能够完成制作。该新型输尿管支架管及磁性拔除导尿管提供了一种微创的、不需影像学引导即可进行拔管的方法,具有良好的应用前景。

Objective To design a novel ureteral stent with a nanoscale iron traction thread at the end and the magnetic catheter,and to assess the feasibility of the innovative removal method.Methods We designed and manufactured the stent and catheter.We tested the properties of them,including:nanoscale iron powder content test of the traction thread by thermo-gravimetric analysis,breaking strength test of the traction thread by tractor,magnetization identification of the magnetic catheter by magnetometer,and magnetic catheter clamping force test.We confirmed the validity of the new removal method through conducting removal experiments in a transparent model of urinary system,which was generated in early study,and calculated success rate and removal resistance.Results The mass fraction of nanoscale iron powder was 23% in the dacron traction thread,the breaking strength of the dacron traction thread was 10.12 N,the magnetization of the magnetic catheter was 578 emu/g,and magnetic catheter clamping force was(10.79±0.84) N.Removal experiments were carried out 50 times,the success rate was 98%,and the mean maximum resistance of removal was(5.26± 0.53) N.Conclusions This study preliminarily confirmed that the innovative removal method was effective,and could be manufactured by existing materials.This offered a minimally invasive method to remove the ureteral stent without image guide.The novel ureteral stent and the magnetic catheter had a bright prospect.

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