北京生物医学工程

___________基于EEG的酒精依赖对脑功能的影响_________

Influences of alcohol dependence on brain function based on EEG

作者：李宁邢丽冬钱志余张玺邓建辉何俊豪于婷婷

单位：           南京航空航天大学自动化学院生物医学工程系(南京210016)<p></p>

关键词：脑电信号；酒精依赖；重心频率；R值

分类号：           R318.04    

出版年·卷·期（页码）：2015·34·6（568-572）

摘要：

目的研究酒精依赖对个体脑电信号的影响,以期了解酒精依赖对个体健康的影响。方法基于亨利（

纽约州立大学）实验所得的102例脑电数据，对数据进行预处理，去除伪迹，提取脑电特征波并计算包含

功率谱、R值和重心频率在内的脑电参数，进行统计学分析，以讨论分析酒精依赖患者与健康人的脑电差

异。结果相对于健康人，酒精依赖患者的脑电中α波相对功率减小，其中以顶区和枕区最为显著。θ波

功率减小，在颞叶的变化较为明显。β波相对功率在各个脑区均大幅提高。全脑区R值均减小，重心频率

均增大。结论相对于健康人群，酒精依赖患者的脑电信号普遍向高频迁移，表明酒精依赖可以使大脑皮

质的兴奋度增强，脑活动更为复杂。

Objective Aiming at studying the influences of alcohol dependence on individual

brain electric signals,we made a comparison between the patients with alcohol dependence and

the healthy control subjects,expecting to get the impact of alcohol on individuals.Methods

One hundred and two cases of EEG data used in this paper were from Henry’s experiment in

State University of New York.After removing the artifact,extracting the EEG feature waves

and calculating the relevant EEG parameters,the statistics analysis was done to analyze the

difference of EEG between alcoholics and healthy control subjects.Results Compared with

healthy control subjects,the alcoholics’ relative power of α band decreased,especially in

parietal and occipital regions.The power of θ band decreased,especially in temporal

region.The power of β band increased in all brain regions.The R-value decreased while the

gravity frequency increased in each region.Conclusions Alcohol dependence makes patients’

EEG signals migrates to the high frequency,increases the excitability of cerebral cortex and

makes brain activities more complicated.

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