石家庄市第四医院超声科(石家庄 050011)
付丽曼。E-mail:563143967@qq.com
收稿:2025-09-26,
修回:2026-03-04,
网络首发:2026-08-17,
纸质出版:2026-08-20
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高曼,陈舜珏,彭艳艳,等.三维能量多普勒超声参数对胎盘植入侵及膀胱的鉴别诊断价值[J].北京生物医学工程,2026,45(4):356-362.
GAO Man,CHEN Shunjue,PENG Yanyan,et al.Value of three-dimensional power Doppler ultrasound parameters in differential diagnosis of placenta accreta invading bladder[J].Beijing Biomedical Engineering,2026,45(4):356-362.
高曼,陈舜珏,彭艳艳,等.三维能量多普勒超声参数对胎盘植入侵及膀胱的鉴别诊断价值[J].北京生物医学工程,2026,45(4):356-362. DOI: 10.3969/j.issn.1002-3208.2026.04.004.
GAO Man,CHEN Shunjue,PENG Yanyan,et al.Value of three-dimensional power Doppler ultrasound parameters in differential diagnosis of placenta accreta invading bladder[J].Beijing Biomedical Engineering,2026,45(4):356-362. DOI: 10.3969/j.issn.1002-3208.2026.04.004.
目的
2
当前,随着胎盘植入的发生率持续升高,但目前血清、超声等方式在评估深度及诊断效能中仍无法满足临床需求,故在此背景上探讨三维能量多普勒超声(three-dimensional power Doppler ultrasound, 3D PDUS)在诊断胎盘植入侵及膀胱的应用价值。
方法
2
取有剖宫产史、前置胎盘并胎盘植入且孕周≥28周的病例130例,将胎盘植入侵及膀胱病例48例归为病例组,将胎盘植入未侵及膀胱病例82例归为对照组。收集患者临床数据、常规超声图像和3D PDUS血流参数血管化指数 (vascular index, VI)、流量指数(flow index, FI)及血管流量指数(vascularization-flow index, VFI),比较3D PDUS参数差异,采用ROC曲线计算曲线下面积,评价VI、FI、VFI对胎盘膀胱植入诊断效能。
结果
2
病例组VI、FI、VFI值分别是33.65%±6.73%、47.36±9.47、17.52±3.51,对照组分别是25.98%±5.19%、43.16±8.63、12.26±2.45,病例组VI、FI、VFI均高于对照组(
P
<
0.05)。VI、FI、VFI对胎盘膀胱植入有一定的诊断价值,ROC曲线数据显示VI截断值为32.565%时,曲线下面积为0.789(95%CI:0.712~0.867),约登指数为47.61,灵敏度为85.42%,特异度为62.20%,阳性预测值为56.15%,阴性预测值为89.23%;FI截断值为44.235时,曲线下面积为0.735(95%CI:0.635~0.834),约登指数为52.18,灵敏度为60.42%,特异度为89.02%,阳性预测值为77.69%,阴性预测值为78.46%;VFI截断值为15.760时,曲线下面积为0.823(95%CI:0.750~0.895),约登指数为49.44,灵敏度为72.92%,特异度为79.27%,阳性预测值为65.38%,阴性预测值为81.54%。
结论
2
3D PDUS定量参数对胎盘膀胱植入有较好的诊断价值,可为其提供有价值的参考信息。
Objective
2
At present, the incidence of placenta accreta continues to rise, but at present, serum, ultrasound and other methods still can not meet the clinical needs in evaluating the depth and diagnostic efficiency. Therefore, this paper discusses the application value of three-dimensional power Doppler ultrasound (3D PDUS) in the diagnosis of placenta accreta invading the bladder.
Methods
2
One hundred and thirty cases with cesarean section history, placenta previa and placenta accreta with gestational age≥28 weeks were selected. Forty-eight cases of placenta accreta invading the bladder were classified as the case group, and 82 cases of placenta accreta not invading the bladder were classified as the control group. The clinical data, conventional ultrasound images and 3D PDUS blood flow parameters including vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were collected. The differences of 3D PDUS parameters were compared. The area under the curve was calculated by ROC curve, and the diagnostic efficacy of VI, FI and VFI for placenta and bladder implantation was evaluated.
Results
2
Case group VI, FI, and VFI values were 33.65%±6.73%, 47.36±9.47, 17.52±3.51, respectively. In the control group, these values were 25.98%±5.19%, 43.16±8.63, and 12.26±2.45, respectively. The VI, FI, and VFI values in the case group were all higher than those in the control group (
P
<
0.05). VI, FI, and VFI demonstrated diagnostic value for placental bladder implantation. The ROC curve analysis showed that at a cut-off value of 32.565% for VI, the area under the curve (AUC) was 0.789 (95% CI:0.712 to 0.867), the Youden index was 47.61, the sensitivity was 85.42%, the specificity was 62.20%, the positive predictive value (PPV) was 56.15%, and the negative predictive value (NPV) was 89.23%.For FI, at a cut-off value of 44.235, the AUC was 0.735 (95% CI:0.635 to 0.834), the Youden index was 52.18, the sensitivity was 60.42%, the specificity was 89.02%, the PPV was 77.69%, and the NPV was 78.46%.For VFI, at a cut-off value of 15.760, the AUC was 0.823 (95% CI:0.750 to 0.895), the Youden index
was 49.44, the sensitivity was 72.92%, the specificity was 79.27%, the PPV was 65.38%, and the NPV was 81.54%.
Conclusions
2
3D PDUS quantitative parameters have good diagnostic value for placenta and bladder implantation, and can provide valuable reference information for it.
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